This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citing articles on HighWire  • Citing articles on Web of Science (14)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Treatment with Ascorbic Acid

LIEUTENANT MILLARD CARNRICK; B. D. POLIS; THOMAS KLEIN, M.D.

Arch Intern Med. 1946;78(3):296-302.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

CYANOSIS is caused most frequently by cardic or pulmonary disease, but it may be the result of an increased concentration of methemoglobin, among other etiologic factors. In the absence of cardiac or pulmonary disease further study of the blood to establish or exclude the presence of this hemoglobin derivative is of considerable importance. We have recently encountered 2 patients presenting cyanosis as an important symptom. In 1 the disease is of unusual interest in that a spontaneous formation of methemoglobin was apparently the cause of the cyanosis. A similar syndrome was described by Stokvis in 1902 and named enterogenous cyanosis.¹ Since that time a few additional reports of spontaneously occurring methemoglobinemia in the absence of drug therapy have been described.² Unfortunately, laboratory examinations of the blood pigments were not always made. In the other patient sodium nitrite therapy was the cause of the cyanosis.

Methemoglobinemia is commonly accompanied . . . [Full Text PDF of this Article]

Author Affiliations
MEDICAL CORPS, ARMY OF THE UNITED STATES; Senior Biochemist, Division of Laboratories, Philadelphia General Hospital; Visiting Physician, Department of Medicine, Philadelphia General Hospital PHILADELPHIA

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?