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A Comparative Clinical Study

LOWELL A. RANTZ, M.D.; PAUL J. BOISVERT, M.D.; WESLEY W. SPINK, M.D.

Arch Intern Med. 1946;78(4):369-386.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

GREAT interest has been aroused in hemolytic streptococcic infection of the respiratory tract during recent years. This has been the result of the demonstration that such infection frequently initiates a complex nonsuppurative process, of which rheumatic fever is the most important and dramatic manifestation. A recent critical study¹ showed that this disease was invariably preceded by a hemolytic streptococcic infection. In spite of this fact, definitive clinical studies of the nature of streptococcic infection of the respiratory tract are almost nonexistent. The Dicks² and Dochez³ established the fact that scarlet fever is caused by hemolytic streptococci and showed that experimental infection in human beings was not always associated with rash formation. An immunologic explanation of this phenomenon was offered. Adequate monographs describing the natural history of scarlet fever are available but deal largely with the disease as observed in children.⁴

The splendid work of Lancefield⁵ . . . [Full Text PDF of this Article]

Author Affiliations
SAN FRANCISCO; NEW HAVEN, CONN.; MINNEAPOLIS

The laboratories of the Department of Medicine, Stanford University School of Medicine, San Francisco, were made available to the Commission for certain purposes.

Footnotes
Col. T. E. Harwood Jr., Major James Blanton and Capt. Howard Coggeshall assisted in the preparation of this paper. Elizabeth Randall, Viola Ferris, Loraine Kerr and Helen Rantz were responsible for the technical and secretarial work.; This investigation was carried out during a field study by the Commission on Hemolytic Streptococcal Infections, Board for the Investigation and Control of Influenza and Other Epidemic Diseases in the Army, Preventive Medicine Service, Office of the Surgeon General, United States Army.

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