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DAVID A. RYTAND, M.D.; LESTER S. LIPSITCH, M.D.

Arch Intern Med. 1946;78(5):544-564.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

CALCIFICATION of the mitral annulus fibrosus has been studied by pathologists¹ and is fairly often discovered more or less accidentally during life by radiologists.² Both groups of observers, properly enough, have regarded it as a degenerative change of no clinical significance.

Yet such calcification is not entirely without clinical interest and was in part the subject of a recent monograph.³ Its occurrence in the older age groups guarantees that it will be associated at least now and then with obvious heart disease⁴; in fact, it has long been known⁵ as one variety of those calcifications which cause heart block.⁶

Then too either the calcification itself or the accompanying valvular changes of aging might reasonably be expected to alter cardiodynamics even in the absence of heart block; practically nothing⁷ has been written about murmurs in its presence, and prominent authors⁸ dismiss it somewhat vaguely as occasionally associated with mitral . . . [Full Text PDF of this Article]

Author Affiliations
SAN FRANCISCO

From the Department of Medicine, Stanford University School of Medicine, San Francisco.

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