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The Course of the Acute Disease

LOWELL A. RANTZ, M.D.; WESLEY W. SPINK, M.D.; PAUL J. BOISVERT, M.D.

Arch Intern Med. 1947;79(3):272-290.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

THE INITIAL phase of acute sore throat caused by group A hemolytic streptococci in young men has been previously described elsewhere.¹ Special attention was paid to the symptoms, signs and results of clinicopathologic and bacteriologic studies. Exudative tonsillitis was a frequent manifestation of streptococcic respiratory disease, but this sign was absent in many cases. Edema of the pharyngeal tissues and tender adenitis in the anterior cervical region were emphasized as abnormalities which were of value in the recognition of infection by hemolytic streptococci. Atypical cases were described, in which no definite evidence of streptococcic infection could be obtained by clinical study in the absence of serial antibody determinations. A cutaneous rash was associated with streptococcic sore throat in only a few cases.

This paper has been prepared for the purpose of recounting the subsequent events which occurred in this group of patients during the initial phase of the disease . . . [Full Text PDF of this Article]

Author Affiliations
SAN FRANCISCO; MINNEAPOLIS; NEW HAVEN, CONN.

Footnotes
The laboratories of the Department of Medicine, Stanford University School of Medicine, were made available to the Commission for certain purposes.

This investigation was carried out during a field study by the Commission on Hemolytic Streptococcal Infections, Board for the Investigation and Control of Influenza and Other Epidemic Diseases in the Army, Preventive Medicine Service, Office of the Surgeon General, United States Army.

The cooperation and assistance of Colonel T. E. Harwood Jr., Major James Blanton and Captain Howard Coggeshall are gratefully acknowledged. The study was made possible by the devoted efforts of Elizabeth Randall, Viola Ferris, Loraine Kerr and Helen Rantz, who were responsible for the technical and secretarial work.

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