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The Poststreptococcic State

LOWELL A. RANTZ, M.D.; PAUL J. BOISVERT, M.D.; WESLEY W. SPINK, M.D.

Arch Intern Med. 1947;79(4):401-435.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

IT HAS been known for more than thirty years that recovery from hemolytic streptococcic infection of the respiratory tract is frequently complicated by the development during convalescence of a variety of disorders including fever, arthritis, carditis and nephritis.¹ These conditions are clearly not the result of a direct invasion of the remote tissues by streptococci present in the throat during the initial illness and may be regarded as "late nonsuppurative complications"² of hemolytic streptococcic disease. The importance of this concept has been emphasized by the increasing body of evidence which indicates that rheumatic fever is one of the late complications of infection by hemolytic streptococci. Recent investigation has greatly increased the information available in regard to the bacteriology, immunology and natural history of streptococcic infection and its complications. In a series of papers³ the pertinent literature has been reviewed, and the clinical manifestations of the intial phase . . . [Full Text PDF of this Article]

Author Affiliations
SAN FRANCISCO; NEW HAVEN, CONN.; MINNEAPOLIS

Footnotes
The laboratories of the Department of Medicine, Stanford University School of Medicine, were made available to the commission for certain purposes.

This investigation was carried out during a field study by the Commission on Hemolytic Streptococcal Infections, Board for the Investigation and Control of Influenza and Other Epidemic Diseases in the Army, Preventive Medicine Service, Office of the Surgeon General, United States Army.

The cooperation and assistance of Col. T. E. Harwood Jr., Major James Blanton and Capt. Howard Coggeshall are gratefully acknowledged. The study was made possible by the devoted efforts of Elizabeth Randall, Viola Ferris, Loraine Kerr and Helen Rantz, who were responsible for the technical and secretarial work.

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