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Report of Nine Patients Treated with Sulfonamide Drugs or Penicillin

COLONEL D. O. WRIGHT; MAJOR EDWIN M. GOLD; CAPTAIN GEORGE JENNINGS

Arch Intern Med. 1947;79(5):510-517.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

STEVENS and Johnson¹ in 1922 described a "new" eruptive fever associated with stomatitis, ophthalmia, cutaneous eruption and constitutional symptoms. This syndrome is usually considered uncommon; we have seen but 15 patients with it out of 115,000 patients admitted to the hospital since September 1942, 6 of whom had only simple catarrhal conjunctivitis and are not included in this report. This syndrome deserves more emphasis because tragic complications of the eyes, consisting of corneal ulceration or panophthalmitis with partial or complete loss of vision, have been frequent in reported cases. Since these severe complications of the eyes did not occur in our 9 patients treated with sulfonamide drugs and/or penicillin, we feel that their cases should be reported.

Stevens-Johnson syndrome has been referred to as erythema multiforme bullosum with involvement of the mucous membranes of the eyes and mouth,² erythema exudativum multiforme with opthalmia and stomatitis³ or severe . . . [Full Text PDF of this Article]

Author Affiliations
MEDICAL CORPS, ARMY OF THE UNITED STATES

From Medical Service, Army Service Force Regional Hospital, Camp Blanding, Fla.

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