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Report of a Case and Experimental Studies

EMMETT B. REILLY, M.D.; EDWARD L. ARTMAN, M.D.

Arch Intern Med. 1948;81(1):1-8.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

CRYPTOCOCCOSIS is a relatively rare disease, approximately 100 cases having been reported to date. It is characterized by invasion of the body by yeastlike organisms which have a special affinity for the lungs and central nervous system. Clinical manifestations are those of a subacute or chronic infection. Pathologically the response of the tissue is similar to that seen in other infectious granulomas.

The disease was first described by Frothingham,¹ who reported its occurrence in a horse. The first report of the disease in man is that of Stoddard and Cutler,² who published their monograph in 1916. There have been numerous reports since that time. Some of the more recent reviews include one by Reeves, Butt and Hammack³ in 1941 and one by Voyles and Beck⁴ in 1946.

The causative organism, Cryptococcus hominis, is widely distributed in nature as a saprophyte. It is a yeastlike organism which reproduces by budding only, without mycelial . . . [Full Text PDF of this Article]

Author Affiliations
LOS ANGELES

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