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FOOD PROTEIN CONSUMPTION IN GLOMERULONEPHRITISEffect on Proteinuria and the Concentration of Serum Protein
EDWARD C. PERSIKE, M.D.;
T. ADDIS, M.D.
Arch Intern Med. 1948;81(5):612-622.
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WITHIN the last decade, few studies have been made of the relationship of consumption of food protein to proteinuria and to concentration of serum protein in glomerular nephritis, although previously many such reports appeared in the literature. Additions to the knowledge of renal pathophysiology during this period, however, offer explanations for phenomena previously unexplained, and contradict some interpretations which have been offered in the past. Certain objections now may be made to the technic employed in some of the older investigations. The therapeutic corollary to this relationship still remains a source for controversy, but much evidence has accumulated to show that attempts at treatment with high protein diets in conditions associated with renal damage may not be helpful, as was previously supposed by some, but may be dangerous. For these reasons, the following experiments were undertaken to demonstrate the effect of varying levels of consumption of food protein on proteinuria
. . . [Full Text PDF of this Article]
Author Affiliations
SAN FRANCISCO
From the Department of Medicine, Stanford University School of Medicine, San Francisco.
Footnotes
Technical assistance was given by Mrs. Evalyn Barrett and Miss Helen J. Ureen.
These experiments were aided by grants from the United States Public Health Service and the Columbia Foundation.
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