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Study of Eleven Cases

FRANCIS R. WHITEHOUSE, M. D.; JAMES W. KERNOHAN, M.D.

Arch Intern Med. 1948;82(1):75-111.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

SINCE 1886, when Hirschsprung¹ published a report entitled ""Sluggishness of the Stool in the Newborn, Resulting from Dilatation and Hypertrophy of the Colon," there have been many reports in the medical literature describing various aspects of megacolon. Generally, the name "Hirschsprung's disease" has been applied to the cases of megacolon reported in the literature but, as Finney² has pointed out, there were many reports of cases of megacolon in the literature antedating those of Hirschsprung. For this reason, in our opinion the descriptive term "megacolon" rather than the less precise eponym should be applied to these cases.

Cases of megacolon are rarely encountered.³ Perhaps as a result of the rarity of the condition, there have been few descriptions of the gross pathologic characteristics of megacolon. There have been a few reports⁴ of single cases of megacolon in which the myenteric plexus was studied by microscopic pathologic methods. Except for the . . . [Full Text PDF of this Article]

Author Affiliations
Fellow in Medicine, Mayo Foundation; ROCHESTER, MINN.

Footnotes
Abridgment of thesis submitted by Dr. Whitehouse to the Faculty of the Graduate School of the University of Minnesota in partial fulfilment of the requirements for the degree of M.S. in Medicine.

Dr. Kernohan is from the Section on Pathologic Anatomy, Mayo Clinic.

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