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SIDNEY ROTHBARD, M.D.; ROBERT F. WATSON, M. D.; HOMER F. SWIFT, M.D.; ARMINE T. WILSON, M.D.

Arch Intern Med. 1948;82(3):229-250.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

NUMEROUS investigators have studied the antibody responses of patients with either complicated or uncomplicated streptococcic infections, but only a few workers¹ have dealt with more than one or two of the antibodies to the known antigenic components of group A hemolytic streptococci. Moreover, reports which have dealt with the antibody response of patients with streptococcic complications and sequelae rarely included the period of the acute streptococcic infection in the study. Antistreptolysin O and antifibrinolysin have been the two antibodies most commonly studied. Todd² originally showed that the serum anti-streptolysin O titer was increased after hemolytic streptococcic infections and during the active stage of rheumatic fever. Tillett, Edwards and Garner³ were the first to show that the plasma clot of most patients convalescent from acute hemolytic streptococcic infections became resistant to lysis by a standard culture of hemolytic streptococci, and Hadfield, Magee and Perry⁴ observed that the . . . [Full Text PDF of this Article]

Author Affiliations
NEW YORK

From the Hospital of The Rockefeller Institute for Medical Research.