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Report of Three Cases

LLOYD D. MAYER, M.D.; IRVING GREENFIELD, M.D.

Arch Intern Med. 1949;84(3):379-388.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

INCIDENCE

The POPULARITY of the barbiturates with the medical profession and the laity has contributed greatly to the pronounced rise in the rate of poisonings and deaths due to their use. In 1946 the city hospitals of New York were reporting 1 death every thirtysix hours due to this type of drug.¹

Of the many barbituric acid derivatives which have been made and introduced to the medical profession, about twenty are used in clinical medicine today. Estimates have indicated that 230,000 pounds of barbiturates were manufactured in 1936, whereas 550,000 pounds, or more than twice as much, were produced in 1945.¹ This alone is indicative of the tremendous increase in the use of these drugs.

As each new drug is developed and detailed to the medical profession, it tends to enjoy a period of popularity. In 1936, the fashionable drug to use was phenobarbital or pentobarbital sodium; in . . . [Full Text PDF of this Article]

Author Affiliations
Resident in Medicine, Montefiore Hospital; Director of Anesthesia, Montefiore Hospital PITTSBURGH

From Montefiore Hospital.

Footnotes
Read at the meeting of the Pittsburgh Anesthesiology Society, March, 1948.

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