This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citing articles on Web of Science (4)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Report of a Case in a Girl of Fourteen

HENRY E. HAMILTON, M.D.; WILLIS M. FOWLER, M.D.

Arch Intern Med. 1949;84(3):445-448.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

PERNICIOUS anemia is a disease of late adult life, rarely being encountered in patients under 30, and is exceedingly infrequent in children. Doubt has been expressed in many texts and articles as to whether true pernicious anemia ever occurs in infancy or childhood. A pernicious anemia-like disease, i. e., a macrocytic anemia with megaloblastic arrest of the bone marrow, may occur with Diphyllobothrium infection, syphilis, various gastrointestinal lesions, steatorrhea, or other conditions in which there is improper absorption or production of the maturation factor.¹ The commonest cause of macrocytic anemia in childhood is probably a diet deficient in the extrinsic factor. There have been many reports of pernicious anemia occurring in children, but the diagnosis was open to question in most cases, and Wintrobe^1b accepted only 2 cases with certainty. Peterson and Dunn,² in 1946, reviewed the literature on the subject; they accepted only 2 cases³ . . . [Full Text PDF of this Article]

Author Affiliations
IOWA CITY

From the Department of Internal Medicine, State University of Iowa College of Medicine.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?