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  Vol. 84 No. 4, OCTOBER 1949 TABLE OF CONTENTS
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SYMPTOMS ATTRIBUTABLE TO COLD HEMAGGLUTINATION

Report of Two Cases

JEANNE C. BATEMAN, M.D.

Arch Intern Med. 1949;84(4):523-531.

Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

THE PHENOMENON of cold hemagglutination was recognized fifty years ago and gave rise to an extensive foreign literature during the first part of this century. Since its relationship to primary atypical pneumonia was pointed out by Peterson, Ham and Finland,1 in 1943, the subject has received considerable attention in this country. Whereas cold hemagglutination was originally regarded as a phenomenon of mainly academic interest, it became increasingly evident not only that it was a valuable diagnostic aid in some epidemics of primary atypical pneumonia but that it could give rise to certain definite symptoms occasionally serious in character and directly related to intravascular hemagglutination. Agglutination of all types of red blood cells at cold temperatures by serum, with reversal at warm temperatures, occurs in a wide variety of conditions.2 Cold hemagglutination appears to be transient in acute infectious diseases, in trypanosomiasis, in acute hemolytic anemia and in some . . . [Full Text PDF of this Article]


Author Affiliations

WASHINGTON, D. C.

Formerly Instructor in Medicine, New York University College of Medicine, and Assistant Visiting Physician, Third Medical Division, Bellevue Hospital.



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