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RENAL OSTEODYSTROPHY ASSOCIATED WITH DIABETES MELLITUSCongenital Polycystic Hypoplasia of the Kidneys and Polycystic Disease of the Pancreas
ALBERT JACKSON, M.D.;
GEORGE C. BATES, M.D.;
MANUEL SLAVIN, M.D.;
M. DONALD McFARLAND, M.D.
Arch Intern Med. 1950;85(1):11-26.
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RECENTLY we had the opportunity to study an unusual case of chronic renal failure, associated with changes in bone suggestive of osteitis fibrosa cystica. The patient had true diabetes mellitus rather than renal glycosuria, which has been described in previous cases. Additional unusual findings at postmortem examination, including polycystic disease of the pancreas, prompted us to present this case with a review of the literature. The triad of chronic nephritis, bony changes in the skeleton and physical dwarfism has been designated as renal rickets.1 This is actually a misnomer in that the bony changes are not those characteristic of rickets and it is not even necessary that rickets be associated with this syndrome,2 although it is sometimes associated with rickets.3 A better term would be renal hyperparathyroidism with osteoporosis, as designated by Park and Eliot,4 renal osteitis fibrosa cystica (Albright and others5) or osteodystrophy (Norman
. . . [Full Text PDF of this Article]
Author Affiliations
Cardiologist, Veterans Administration Center; Resident in Pathology, Veterans Administration Center; Chief, Department of Internal Medicine, Veterans Administration Center; Consultant in Medicine, Veterans Administration Center WADSWORTH, KAN.
Footnotes
Published with permission of the Chief Medical Director, Department of Medicine and Surgery, Veterans Administration, who assumes no responsibility for the opinions expressed or conclusions drawn by the authors.
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