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VERNON KNIGHT, M.D.; FRANCISCO RUIZ SÁNCHEZ, M.D.; AMADO RUIZ SÁNCHEZ, M.D.; SELMA SHULTZ, M.A.; WALSH McDERMOTT, M.D.

Arch Intern Med. 1950;85(1):44-82.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

DURING the summer of 1948, an investigation of the antimicrobial therapy of typhoid was started in Guadalajara, México The study was conducted as a joint project between investigators from the University of Guadalajara and the New York Hospital—Cornell University Medical College. Three drugs were studied: polymyxin B, aureomycin, and chloramphenicol.¹ Ample clinical and laboratory facilities were available at the Hospital Civil, the teaching hospital for the University of Guadalajara. Nevertheless, it was necessary to study approximately one half of the series of patients in their homes in the city or in the neighboring villages because of the reluctance of some patients to enter any hospital. During the period of the study, a total of 51 patients with typhoid were treated with one of these drugs. Six of the series were treated in New York city² and 3 in Mexico D. F., Mexico, by the same group of investigators. . . . [Full Text PDF of this Article]

Author Affiliations
Postdoctorate Research Fellow, National Institutes of Health, United States Public Health Service NEW YORK; GUADALAJARA, JALISCO, MÉXICO; NEW YORK

From the Department of Medicine of the New York Hospital—Cornell University Medical College and the Institute for the Experimental Study of Infections of the University of Guadalajara, Jalisco, Mexico.

Footnotes
Read in part before the Association of American Physicians, Atlantic City, N. J., May 3, 1949.

This study was supported by grants from The Division of Research Grants and Fellowship, National Institutes of Health, United States Public Health Service; the Lederle Laboratories Division, American Cyanamid Company, Pearl River, N. Y.; and Chas. Pfizer & Company, Brooklyn.

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