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  Vol. 86 No. 1, JULY 1950 TABLE OF CONTENTS
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ALKAPTONURIA, OCHRONOSIS, ARTHRITIS AND RUPTURED INTERVERTEBRAL DISK

Complicated by Homologous Serum Reaction

HARRY EISENBERG, M.D.

Arch Intern Med. 1950;86(1):79-86.

Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

ALKAPTONRIA was recognized in clinical medicine as early as - the sixteenth century. It is true that the evaluation of the clinical findings had to wait for further investigation at a later date; yet the remarkable powers of observation of early workers are dramatically interesting. A descriptive passage by Garrod1 concerning a case reported by Lusitanus2 in 1649 is worthy of repetition.

The patient was a boy who passed black urine and who at the age of fourteen years was submitted to a drastic course of treatment which had for its aim the subsiding of the fiery heat of the viscera which was supposed to bring about the condition in question by charring and blackening his bile. Among the measures prescribed were bleedings, purgative baths, a cold and watery diet and drugs galore. None of these had an obvious effect and eventually the patient who tired of the futile . . . [Full Text PDF of this Article]


Author Affiliations

BUTLER, PA.


Footnotes

Sponsored by the Veterans Administration and published with the approval of the Chief Medical Director. The statements and conclusions published by the author are the result of his own study and do not necessarily reflect the opinion or policy of the Veterans Administration.



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