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  Vol. 86 No. 3, SEPTEMBER 1950 TABLE OF CONTENTS
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NITROGEN SHIFT IN CANCER

JEANNE C. BATEMAN, M.D.

Arch Intern Med. 1950;86(3):355-360.

Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

TISSUE common observation. Weight loss, however, does not always appear early in cancer. Other signs of deranged nitrogen metabolism, such as hypoproteinemia, may persist for some time while synthesis of tissue proteins is taking place.1 The study here reported was undertaken in an attempt to explore further the shifts in nitrogen utilization occurring in patients with neoplastic disease, especially when protein hyperalimentation was employed.

EXPERIMENTAL STUDIES

Material.

—Two patients from the Third Medical Division at Bellevue Hospital, New York, were studied, the first for one period, the second for four periods. H. W. was a 51 year old Chinese man with bronchogenic carcinoma which had been diagnosed by biopsy of a supraclavicular node. There were widespread metastases to ribs, vertebrae, pelvic bones and lymph nodes. The course was rapidly downhill and the twenty-one day study period was terminated by death.

The second patient, a 70 year old white man, . . . [Full Text PDF of this Article]


Author Affiliations

WASHINGTON, D. C.


Footnotes

This study was aided by a grant from the National Institute of Health.

Dr. Bateman was formerly instructor in medicine at New York University College of Medicine and assistant visiting physician on the Third Medical Division at Bellevue Hospital. She is now Research Fellow at the National Cancer Institute, Bethesda, Md.



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