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  Vol. 86 No. 5, NOVEMBER 1950 TABLE OF CONTENTS
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EFFECTS OF TERRAMYCIN ON THE BACTERIAL FLORA OF THE BOWEL IN MAN

JOSEPH M. DI CAPRIO, M.D.; LOWELL A. RANTZ, M.D.

Arch Intern Med. 1950;86(5):649-657.

Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

THE PRESENT study was primarily undertaken to determine the action of terramycin1 on the bacterial flora of the bowel in man, particularly in the presence of ulcerative lesions of that organ.

METHODS

Stool specimens were collected in clean, wax-coated cardboard containers and cultured the same day. They were obtained before and within 36 hours after the institution of therapy in every instance, and at varying intervals thereafter depending on the nature of the case. A total of 44 stool specimens was examined.

There were two objectives in the cultural study: to make a quantitative, as well as qualitative, determination of the micro-organisms present in the stool, and to determine the in vitro sensitivity to penicillin, dihydrostreptomycin and terramycin of the micro-organisms identified. The procedure was as follows: One milliliter of wet stool was added to 9 ml. of sterile isotonic sodium chloride solution and stirred to make a 1:10 . . . [Full Text PDF of this Article]


Author Affiliations

SAN FRANCISCO

From the Department of Medicine, Stanford University School of Medicine.


Footnotes

Miss Gail Reeves and Miss Anne Zuckerman assisted in this study. Drs. Emile F. Holman, Robert A. Scarborough, Russell R. Klein, Clyde C. Greene Jr. and Claude P. Callaway made available some of the patients included in this study.



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