This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

MARVIN SEIFE, M.D.; BRUCE J. KESSLER, M.D.; JAMES R. LISA, M.D.

Arch Intern Med. 1950;86(5):658-670.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

THE DEVELOPMENT and increased use of the needle biopsy technic for the purpose of obtaining specimens of the liver have widened the field for the study of hepatic disease.¹ Among the published investigations several are concerned with the hepatic changes observed in alcoholism.² The purpose of this communication is to present the clinical, functional and histologic observations on a group of alcoholic patients and to describe the histologic changes in the liver noted at short intervals in the absence of specific therapy. Patients with obviously far advanced hepatic disease were excluded in the hope that early or limited lesions might be observed and their possible significance evaluated.

MATERIAL AND METHODS

Sixty-three patients who entered the hospital because of acute alcoholism were observed. Two were studied on two separate occasions. With few exceptions these patients were also chronic alcoholics. In most patients there were no physical signs indicative of . . . [Full Text PDF of this Article]

Author Affiliations
With the Technical Assistance of Frank Scudero, B.S. (Chem.), and Alida J. Ruiz, A.B. NEW YORK

From the First Medical Division and the Laboratory of Pathology, City Hospital, Welfare Island.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?