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Alterations in Cardiac Function

S. J. WEINBERG, M.D.; J. R. GOODMAN, Ph.D.; M. C. BUSHARD, M.D.

Arch Intern Med. 1950;86(6):857-871.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

THE QUESTION of the relationship between the central nervous system and the kidney is of great significance and involves not only somatic vasomotor and endocrine shifts in water balance 1 but possibilities in nephritis as well. In previous experiments on the unanesthetized dog, purely central nervous stimuli, osmotic, alkaloidal and hormonal, were shown² to produce drastic alterations in renal function, including albuminuria and hematuria. The clinical experiments hereafter detailed attempt primarily to demonstrate whether analogous changes occur in man following a purely central nervous stimulus. The evidence for direct relationship between brain and heart has been previously summarized,³ and electrocardiographic changes after pneumoencephalography have been demonstrated.⁴ In our patients studied by ventriculography and pneumoencephalography electrocardiographic analyses were coincidentally obtained.

The occasional occurrence of an oliguria following ventriculography and encephalography leads one to believe that a direct relationship may exist between central nervous stimulation and total suppression of . . . [Full Text PDF of this Article]

Author Affiliations
LOS ANGELES

From the Departments of Medicine and Neurosurgery, Wadsworth General Hospital, and the Brentwood Neuropsychiatric Hospital, United States Veterans Administration Center, and the Department of Medicine, University of California School of Medicine, Los Angeles.

Footnotes
Reviewed by the Veterans Administration and published with the approval of the Chief Medical Director. The statements and conclusions published by the authors are the result of their own study and do not necessarily reflect the opinion or policy of the Veterans Administration.

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