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Sixteenth Annual Review of Significant Publications

HOBART A. REIMANN, M.D.

AMA Arch Intern Med. 1951;87(1):128-174.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

ANTIBIOTICS

NUMEROUS substances widely used at present are penicillin, streptomycin, neomycin, terramycin, chloramphenicol (chloromycetin®), polymyxin (aerosporin®) and bacitracin. Thus far, several newly discovered ones have not extended the range of antibacterial effect greatly. Bacillomycin, prodigiosin¹ and fracidin² are antifungal but have had little or no clinical trial. No effective antiviral agents have been discovered. With the introduction of each new antibiotic agent discrimination must be made between its possible actual superior value and its commercial expediency. It is surprising that, up to now, no commercial interests have exploited the possibility of preparing a combination of antibiotics designed to cure all infectious diseases without the need for bothering with diagnoses. One could even propose a name for it—multimycetin. Perhaps one deterrent is the different routes of administration appropriate for the various antibiotics. Another reason may rest on a demonstration of antagonism between penicillin and chloramphenicol, as measured by their . . . [Full Text PDF of this Article]

Author Affiliations
PHILADELPHIA

From the Jefferson Medical College and Hospital.

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