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DIAGNOSTIC AND THERAPEUTIC USE OF RADIOACTIVE IODINE
DWIGHT E. CLARK, M.D.;
OTTO H. TRIPPEL, M.D.;
GLENN E. SHELINE, M.D.
AMA Arch Intern Med. 1951;87(1):17-24.
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THE NATURE of the radiations from the iodine isotope, I131, makes it valuable as a source of internal radiation for those tissues which will selectively absorb iodine. Although this radioactive isotope emits both beta and gamma rays, the great majority of the biologic activity is due to the beta particles which are entirely absorbed within a distance of about 2 mm. in tissue. In fact, most of the beta rays travel considerably less than 2 mm. Because the beta energy is absorbed so close to its source, intense local radiation effect occurs wherever I131 is concentrated and is limited to this range. The gamma radiation penetrates farther through the tissues. and much of it escapes from the body. The effect which the gamma rays do have on the tissues is thus distributed widely. Consequently, the gamma radiation effect in any area is relatively small. Since gamma rays escape
. . . [Full Text PDF of this Article]
Author Affiliations
CHICAGO
From the Department of Surgery of the University of Chicago.
Footnotes
Atomic Energy Commission Postdoctoral Research Fellow in the Medical Sciences of the National Research Council.
Read in the General Scientific Meetings of the Ninety-Ninth Annual Session of the American Medical Association, San Francisco, June 26, 1950.
The radioactive iodine used in this investigation was supplied by the Oak Ridge National Laboratories, Oak Ridge, Tenn., and obtained under allocation from the United States Atomic Energy Commission.
This work was aided in part by the Charles H. and Mary F. S. Worcester Memorial Fund, by an institutional grant from the American Cancer Society and by a grant from the United States Public Health Service (National Cancer Institute).
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