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Edited by Cosmo G. Mackenzie. Price, $2.70. Pp. 146. Josiah Macy, Jr., Foundation, 565 Park Ave., New York 21, 1949.

AMA Arch Intern Med. 1951;87(1):176-177.

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This volume contains the transactions of the third conference concerned with biologic antioxidants. The participants included persons interested in oxidation or inhibition of oxidation. Compounds considered from the standpoint of their inhibitory effects on oxidation included the naphthoquinones and hydroquinones. The pharmacologic properties of these compounds were considered, as well as their inhibition of oxidation. Recent developments in the chemistry and metabolism of a potent physiological antioxidant, namely, vitamin E, are likewise presented. The possible role of the tocopherols in prevention of certain types of hepatic injury was pointed out, along with the suggestion that such protection may be afforded by means of oxidation-reduction systems. The antioxidant properties of estrogens and androgens were also discussed. The mechanism of action of lipoxidase, an enzyme concerned in the oxidation of fatty acids, was also discussed. This volume represents recent advances in the field of metabolism concerned with antioxidants and will be of . . . [Full Text PDF of this Article]

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