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RADIOACTIVE IODINE IN THE TREATMENT OF HYPERTHYROIDISM
E. PERRY McCULLAGH, M.D.;
CHARLES E. RICHARDS, M.D.
AMA Arch Intern Med. 1951;87(1):4-16.
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HERTZ AND Roberts1 in 1942 published the first report of patients treated with radioactive iodine. Although the results are difficult to interpret because of the almost simultaneous administration of I127, their work forms a landmark in the medical application of the radioactive isotopes to the treatment of disease.
Early studies on both thyroid physiology and treatment of thyroid disease were accomplished by the use of the 12 hour isotope I130.2 In 1946 the availability of radioactive isotopes from the uranium chain-reacting pile was announced, and easy accessibility of the eight day isotope was made possible. The fact that I130 would be displaced in treatment by I131 was recognized by Soley when he stated at the meetings of the American Goiter Association in 1949, "I have omitted the use of I130. the 12.5 hour isotope, because probably it will no longer have a role in this type of
. . . [Full Text PDF of this Article]
Author Affiliations
CLEVELAND
From the Cleveland Clinic and the Frank E. Bunts Educational Institute.
Footnotes
Read before the Section on Experimental Medicine and Therapeutics at the Ninety-Ninth Annual Session of the American Medical Association, San Francisco, June 29, 1950.
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