
ALLERGIC GRANULOMA OF THE LUNGClinical and Anatomic Findings in a Patient with Bronchial Asthma and Eosinophilia
JOSEPH C. EHRLICH, M.D.;
ALFRED ROMANOFF, M.D.
AMA Arch Intern Med. 1951;87(2):259-268.
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THE ALLERGIC basis of certain granulomatous alterations in tissue is receiving increasing recognition, although many of the entities are still ill defined and much of the evidence is indirect. Adequate criteria exist for the identification on morphological grounds of suspected lesions, and there is often satisfactory correlation with the clinical picture. Churg and Strauss1 used the term "allergic granulomatosis" to characterize a group of vascular and extravascular lesions occurring in periarteritis nodosa in association with bronchial asthma and hypereosinophilia. Other cases on record2 probably belong to the same category. Anatomic changes conforming to the general category of allergic reactions in tissue have, furthermore, been described in the lungs in those rare instances of Loeffler's disease which were studied at autopsy.3
In the following report of a case, allergic granulomas of the lung were observed at autopsy in a man who died of asphyxia 10 days after his
. . . [Full Text PDF of this Article]
Author Affiliations
NEW YORK
From the Department of Laboratories and the Medical Service, Lebanon Hospital.
Footnotes
This study was aided by a grant from the Aaron W. Davis Foundation.
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