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EOSINOPHILIC LEUKEMIA WITH REPORT OF A CASE

WILLARD J. CARMEL, M.D.; ALEXANDER M. MINNO, M.D.; W. LEIGH COOK, Jr., M.D.

AMA Arch Intern Med. 1951;87(2):280-286.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

EOSINOPHILIC leukemia or so-called myeloid leukemia with pronounced eosinophilic predominance is an extremely rare disorder. A review of the literature reveals considerable hesitancy to admit its existence as a distinct clinical entity. Its separate identity has been questioned in the reported cases because of the relative maturity of eosinophils in the peripheral blood arid bone marrow, as contrasted with the large numbers of immature cells observed in the more familiar forms of leukemia. As a further difficulty, in chronic myeloid leukemia especially, there is often a relative increase in eosinophils, both mature and immature. Traditionally, there has been slowness to accept other forms of leukemia when first described. The existence of monocytic leukemia is still denied by some observers.

In 1912 Stillman¹ presented the first case of myeloid leukemia with predominance of eosinophilic cells. Since then, approximately 25 similar cases have been described in the form of single case . . . [Full Text PDF of this Article]

Author Affiliations
ASPINWALL, PA.; ROCHESTER, MINN.; PITTSBURGH

From Medical Service, Veterans Administration Hospital, Aspinwall, Pa., and the University of Pittsburgh School of Medicine.

Footnotes
Reviewed by the Veterans Administration and published with the approval of the Chief Medical Director. The statements and conclusions published by the authors are the result of their own study and do not necessarily reflect the opinion or policy of the Veterans Administration.

Drs. Carmel and Minno were formerly Residents in Internal Medicine, Veterans Administration Hospital, Aspinwall, Pa. Dr. Cook is Attending Physician, Internal Medicine, Veterans Administration Hospital, Aspinwall, Pa., and Assistant Professor of Medicine, University of Pittsburgh School of Medicine. Dr. Minno is now a Fellow in Medicine, Mayo Foundation.

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