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TITRATED, REGULARLY SPACED RADIOACTIVE PHOSPHORUS OR SPRAY ROENTGEN THERAPY OF LEUKEMIAS
EDWIN E. OSGOOD, M.D.
AMA Arch Intern Med. 1951;87(3):329-348.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
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THE EVALUATION of a new therapy for chronic leukemias is difficult because of the diverse course of untreated patients, the differing stages of the disease when patients are first seen by a physician, the frequent uncertainty concerning the correct date of onset and the presence of other variables making comparison with published data on other series of patients less satisfactory than the ideally designed experiment. Yet, with a treatment that seems to be giving comfort and years of essentially normal living, the use of alternate or randomly selected, untreated controls in so serious a disease seems unjustified.
It is the purpose of this paper to present the principles of a treatment in use since 1941 in sufficient detail that others may be able to use it and to present enough of the evidence of its merits that others may choose to aid in its final evaluation. This of necessity will
. . . [Full Text PDF of this Article]
Author Affiliations
PORTLAND, ORE.
From the Division of Experimental Medicine, Department of Medicine, University of Oregon Medical School.
Footnotes
Read before the Second Congress of the International Society of Hematology, Aug. 23, 1950, in Cambridge, England.
This work was supported in part by Grants-in-Aid from the Medical Research Foundation of Oregon, the Damon Runyon Cancer Research Fund, Mr. John C. Higgins and the American Cancer Society on recommendation of the Committee on Growth of the National Research Council. The P32 used in this investigation was supplied by Clinton Laboratories, Knoxville, Tenn., and obtained on allocation from the Isotopes Division, United States Atomic Energy Commission.
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