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PSEUDOMONAS MENINGITISReport of a Case with Recovery After Polymyxin B Therapy
CLYDE E. TOMLIN, M.D.
AMA Arch Intern Med. 1951;87(6):863-867.
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PSEUDOMONAS aeruginosa (Bacillus pyocyaneus) is commonly considered an organism of low pathogenicity. Although it lacks invasive properties and is usually a relatively avirulent contaminant of wounds, numerous reports of severe or fatal infections caused by this bacterium attest to its potential danger. Possible sources of infection with Pseudomonas have been syringes and needles,1 penicillin solutions,2 catheterization equipment, distilled water,3 boric acid solution,4 analgesics, a mercury manometer used in spinal puncture5 and, in one case, a wash bottle used in performing a pneumoencephalogram.6 The pathogenic importance of Ps. aeruginosa has increased recently as a result of the widespread use of antibiotics which suppress gram-positive organisms, thus producing unusually favorable conditions for growth of gram-negative bacteria.
Meningitis caused by Ps. aeruginosa is often characterized by an indolent, chronic course. This type of meningitis may occur as a localized inflammation of the meninges, after lumbar puncture or trauma to the
. . . [Full Text PDF of this Article]
Author Affiliations
EMORY UNIVERSITY, GA.
From the Medical Service, Lawson Veterans Administration Hospital, Chamblee, Ga., and the Department of Medicine, Emory University School of Medicine, Atlanta, Ga.
Footnotes
Reviewed in the Veterans Administration and published with the approval of the Chief Medical Director. The statements and conclusions published by the author are the result of his own study and do not necessarily reflect the opinion or policy of the Veterans Administration.
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