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A RATIONAL BASIS FOR THE USE OF LOW SODIUM, HIGH PROTEIN DIET THERAPY IN LAENNEC'S CIRRHOSIS
ROBERT M. KARK, B.A.;
ROBERT W. KEETON, M.D.;
NATHANIEL O. CALLOWAY, Ph.D., M.D.;
GORDON R. MOREY, M.D.;
ROBERT A. CHAPMAN, M.D.;
ROBERT H. KYLE, M.S.
AMA Arch Intern Med. 1951;88(1):61-77.
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DURING the past three years clinical and metabolic studies1 on patients with Laennec's cirrhosis have demonstrated the value of diets high in protein and calories and low in sodium in the management of this disease. Diet therapy is only one part of the total regimen; other important features are rest, general supportive therapy and prohibition of alcohol and hepatotoxic drugs. All these are necessary to protect the liver from further damage, speed regeneration of hepatic cells, correct tissue wasting and restore hormonal and metabolic aberrations to normal. From the practical point of view it is not easy for the dietitian to provide a palatable high protein diet which is low in sodium without the use of special low sodium protein preparations. It appears, however, that this difficulty may be overcome by the oral use of ion exchange resins,2 which absorb large amounts of sodium from the bowel and
. . . [Full Text PDF of this Article]
Author Affiliations
M.R.C.P.(Lond.); CHICAGO
From the Department of Medicine, University of Illinois College of Medicine, the Research and Educational Hospitals and the Medical Nutrition Laboratory, an installation under the jurisdiction of the Surgeon General, United States Army.
Footnotes
The opinions expressed in this paper are those of the authors and do not necessarily represent the official views of any governmental agency.
Read before the Section on Internal Medicine at the Ninety-Ninth Annual Session of the American Medical Association, San Francisco, June 28, 1950.
This study was supported in part by grants to the University of Illinois from the Abbott Laboratories, North Chicago, Ill., and from the National Heart Institute of the Institutes of Health of the United States Public Health Service.
The human albumin used in this study was processed by the American National Red Cross from blood which it collected from voluntary donors. This is one of a series of investigations on human albumin being carried out with material supplied by the American National Red Cross. As soon as sufficient data become available to justify final conclusions concerning its therapeutic value, a full report to the medical profession on the use of human albumin in medical practice will be published.
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