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I. Particle Size

T. ADDIS, M.D.; EVALYN BARRETT; L. G. POO; HELEN UREEN, M.S.

AMA Arch Intern Med. 1951;88(3):337-345.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

WHEN PROTEIN is detected in the urine of patients, we usually find in the urinary sediment direct evidence that a renal lesion exists. During life the development of this lesion can be followed, and after death our inferences concerning the nature of the lesion can be confirmed, corrected and extended by histological examination of the kidney. The disorders of these patients are all instances of what we may call renal proteinuria.

Every now and then, however, we see patients in whose urine protein appears in large amounts, although, at least in the beginning, there is no evidence in the urinary sediment of a renal lesion of any sort. To distinguish these proteinurias from those that develop in association with a renal lesion, we propose to call them "prerenal," this term indicating our supposition that they have their immediate origin in an abnormality, not of the kidney, but of the protein . . . [Full Text PDF of this Article]

Author Affiliations
SAN FRANCISCO

From the Department of Medicine, Stanford University School of Medicine.

Footnotes
Dr. Addis died June 4, 1949.

This work was made possible by a grant from the United States Public Health Service. Part of it was carried out under a grant from the Committee on Medical Research of the Office of Scientific Research and Development.

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