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PRERENAL PROTEINURIAIII. Electrophoretic Studies
ELOISE JAMESON, Ph.D.;
T. ADDIS, M.D.
AMA Arch Intern Med. 1951;88(3):350-355.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
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ELECTROPHORETIC studies were carried out on the proteins from serum and urine of patients who suffered from what has been described previously as prerenal proteinuria.1 In each case the rate of protein excretion was very large. Two patients were followed for six months or more during both exacerbation and remissions of their disease. During episodes of proteinuria, two albumins, split globulins and a low gamma globulin were found in either the serum or the urine, and sometimes in both. The reappearance of the albumin as a single fraction was the first sign of recovery from the proteinuria, the split globulin persisting until the edema was gone. Abnormalities of the electrophoretic pattern of the serum proteins of the one patient studied in this respect were lessened by the addition of human gamma globulin to the serum.
EXPERIMENTAL METHODS AND RESULTS
Method.
—The serum to be studied was diluted to about
. . . [Full Text PDF of this Article]
Author Affiliations
SAN FRANCISCO
From the Department of Medicine, Stanford University, San Francisco, and Institute for Medical Research, Cedars of Lebanon Hospital, Los Angeles.
Footnotes
Dr. Jameson is now at the University of Southern California, Los Angeles.
Dr. Addis' death occurred on June 4, 1949, before this paper was completed.
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