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Review of the Literature and Report of Three Cases

MAXWELL SPRING, M.D.; SIDNEY KAHN, M.D.

AMA Arch Intern Med. 1951;88(3):373-377.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

ALL OF us are familiar with gas gangrene, the infection produced by Clostridium perfringens (Bacillus welchii). However, very few of us know that other organisms, such as Escherichia coli and anaerobic Streptococcus, can also produce gas infection in tissues.

In 1825 Boismont¹ first mentioned the spontaneous production of gas in the urinary bladder. He considered it to be a secretion by the mucosa. Chomel² added the suggestion that the gas might be due to fermentation. Guiard³ first pointed out the occurrence of pneumaturia in diabetic persons in 1883 and reported four cases. In 1888 Favre⁴ isolated a gas-forming bacterium from the urine of a nondiabetic person who died. Chiari⁵ in 1893 was the first to describe the formation of gas due to the colon bacillus in the gangrenous tissues of the leg of a diabetic. Animal inoculation with the organism failed to produce gas. He . . . [Full Text PDF of this Article]

Author Affiliations
NEW YORK

From the Medical and Surgical Service of The Bronx Hospital.

Footnotes
Read Before the Meeting of the Clinical Society of The New York Diabetic Association at the New York Academy of Medicine, New York, Feb. 8, 1951.

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