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STUDIES IN MITRAL STENOSISII. A Correlation of Post-Mortem Findings with the Clinical Course of the Disease in One Hundred One Cases
GARTH K. GRAHAM, M.D.;
JAMES A. TAYLOR, M.D.;
LAURENCE B. ELLIS, M.D.;
DAVID J. GREENBERG, M.D.;
STANLEY L. ROBBINS, M.D.
AMA Arch Intern Med. 1951;88(4):532-547.
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WITH THE development of surgical technics for the relief of mitral stenosis which promise to be both effective and not unreasonably hazardous, it has become important to reassess this syndrome in regard to various pathologic factors that may affect the clinical course of the disease and have a bearing on the selection of patients for operation. Among such factors, the interrelations between the degree of stenosis, the presence of organic pulmonary vascular lesions, the occurrence of emboli, and rheumatic activity, and the manner in which cardiovascular breakdown and death occur are important. This study was undertaken with these points in view.
MATERIALS AND METHODS
Cases studied were from the post-mortem files of the Mallory Institute of Pathology, of the Boston City Hospital, between January, 1945, and June, 1949, and include the autopsy and clinical records of all patients whose conditions was diagnosed at post-mortem examination during this period as rheumatic
. . . [Full Text PDF of this Article]
Author Affiliations
BOSTON
From the Thorndike Memorial Laboratory, Second and Fourth Medical Services (Harvard), Boston City Hospital, and the Department of Medicine, Harvard Medical School.
Footnotes
Dr. Graham is National Heart Institute Trainee.
This investigation was supported in part by research grants from the National Heart Institute of the National Institutes of Health, United States Public Health Service, and from the Life Insurance Medical Research Fund.
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