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Lesions of Rectum and Sigmoid Colon Which Clinically Simulated Cancer but Which Responded to Aureomycin Therapy

MARTIN S. BELLE, M.D.; SIDNEY FOX, M.D.; RALPH ALLEN, M.D.

AMA Arch Intern Med. 1951;88(5):685-691.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

ADISCUSSION of the etiological basis for benign granulomatous lesions of the rectum and sigmoid colon usually includes lymphogranuloma venereum, syphilis, tuberculosis, amebiasis, gonorrhea, and schistosomiasis.¹ One encounters infrequently such lesions in a medical ward in a general hospital or in the practice of internal medicine. The differential diagnosis between a benign and a carcinomatous lesion is sometimes difficult. In view of this fact we thought it important to record our experience with two patients who presented this problem.

Two cases of granulomatous lesion of the rectum and sigmoid have been observed. From historical data and the results of physical examination, including proctosigmoidoscopy, the lesions were thought to be malignant, but after thorough study, including biopsy, they were proved to be nonspecific granulomas. The response of these lesions to aureomycin therapy was unexpected and most unusual and saved the patients from a resection of the colon and rectum that would . . . [Full Text PDF of this Article]

Author Affiliations
CORAL GABLES, FLA.

From the Veterans Administration Hospital.

Footnotes
Dr. Belle is attendant in internal medicine.

Dr. Fox is former senior resident in internal medicine.

Dr. Allen is attendant in proctology.

Sponsored by the Veterans Administration and published with the approval of the Chief Medical Director. The statements and conclusions published by the authors are a result of their own study and do not necessarily reflect the opinion or policy of the Veterans Administration.

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