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HYPOCELLULAR MARROW IN ACUTE LEUKEMIAReport of Two Cases
MILTON R. BEYERS, M.D.;
LEO M. MEYER, M.D.;
MARTIN LOWENTHAL, M.D.;
ROBERT J. OEHRIG, M.D.;
ARTHUR SAWITSKY, M.D.
AMA Arch Intern Med. 1951;88(6):803-811.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
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IN ACUTE leukemia, with or without peripheral leucocytosis, sternal-marrow aspiration by the Arinkin technique characteristically reveals marked hyperplasia with a predominance of immature "blast" cells.1 Because of this usually typical picture, marrow study is of particular importance in differentiating cases of acute leukemia without peripheral leucocytosis from cases of aplastic anemia and granulocytopenia.
We are reporting two cases of acute leukemia with peripheral leucopenia which are atypical in that the patients presented hypocellular marrows rather than the usual hypercellularity. One patient had persistent leucopenia and a hypoplastic marrow throughout his course. The other, during a relapse following cortisone therapy, had hypercellular marrow with associated leucocytosis.
REPORT OF CASES
CASE 1.
—This was the first admission (July 10, 1950) to the Bronx Veterans Administration Hospital of a 63-year-old married white male bridge operator, with the chief complaint of painless "swollen glands" of three months' duration. These enlarged lymph nodes first
. . . [Full Text PDF of this Article]
Author Affiliations
NEW YORK
From the Department of Internal Medicine, Veterans Administration Hospital, Bronx, N. Y., and the Third New York University Medical Service, Goldwater Memorial Hospital, New York.
Footnotes
Reviewed in the Veterans Administration and published with the approval of the Chief Medical Director. The statements and conclusions published by the authors are a result of their own studies and do not necessarily reflect the opinion or policy of the Veterans Administration.
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