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USE OF CORTICOTROPIN AND CORTISONE IN ACUTE HOMOLOGOUS SERUM HEPATITIS
HAROLD RIFKIN, M.D.;
LEON J. MARKS, M.D.;
DAVID J. HAMMERMAN, M.D.;
MORTIMER J. BLUMENTHAL, M.D.;
ALTER WEISS, M.D.;
BERTHOLD WEINGARTEN, M.D.
AMA Arch Intern Med. 1952;89(1):32-40.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
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THE ABILITY of the physician to treat liver disease on any rational basis has probably made little progress in the last century.1 The doctor's resources in the therapy of acute hepatitis include rest in bed, forced high-protein and high-carbohydrate intake, administration of lipotropic agents, liver extract, and multiple vitamins, and parenteral fluid alimentation, including use of salt-poor albumin.2 With early diagnosis and institution of therapy, many patients will recover from the acute stage of the disease. Experience has demonstrated, however, that a number of these patients will die of an acute rapidly progressive hepatitis and cholemia. These patients usually become anorectic, with severe nausea and vomiting. Parenteral alimentation becomes difficult, especially when the patient is confused and disoriented. It is imperative, therefore, to obtain some agent which will provide support until the liver can repair itself. Eppinger in Europe3 and recently Webster4 in this country have utilized adrenal cortex extract
. . . [Full Text PDF of this Article]
Author Affiliations
NEW YORK
From the Medical Division, Dr. Louis Leiter, Chief, Montefiore Hospital.
Footnotes
Dr. Marks and Dr. Hammerman and Dr. Blumenthal are Assistant Residents, Medical Division, Montefiore Hospital.
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