
KLEBSIELLA PNEUMONIAE MENINGITISReview of the Literature and Report of a Case with Bacteremia and Pneumonia, with Recovery
ALVIN J. THOMPSON, M.D.;
EDWARD B. WILLIAMS, Jr., M.D.;
EDWIN D. WILLIAMS, M.D.;
JOHN M. ANDERSON, B.S.
AMA Arch Intern Med. 1952;89(3):405-420.
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KLEBSIELLA pneumoniae (Friedländer's bacillus) meningitis is one of the less common forms of meningeal infection. Its rarity requires continued case analysis and reviews of the literature for its more accurate clinical description. The advent of the antibiotics and the increased possibility of cures suggest a reevaluation of therapeutic measures.
The bacillus was first identified by Friedländer in 1882, and the first case of meningitis due to this organism was reported by Weichselbaum in 1888. Thereafter, reports of K. pneumoniae meningitis were sporadic. In 1943 Ransmeier and Major1 collected 30 cases from the literature. In 1949 Sadusk, and associates2 assembled 54 instances of the infection; only 5 of the patients recovered. Bombardier's3 extensive review in 1950 disclosed 72 cases of meningitis due to this organism. In this communication 118 cases of K. pneumoniae meningitis, including 31 with recovery, gathered from the world's literature to date are reviewed. One
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Author Affiliations
ST. LOUIS
From the Medical Service of the Homer G. Phillips Hospital and the Department of Medicine of the Washington University School of Medicine.
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