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ACUTE HEMOLYTIC ANEMIA ASSOCIATED WITH MYELOID METAPLASIA OF THE SPLEENReport of a Case Treated by a Splenectomy
MAURICE A. CLAMAN, M.D.;
WILLIAM J. COLLIER, M.D.
AMA Arch Intern Med. 1952;89(3):431-435.
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SINCE the description of Jackson and associates1 of myeloid metaplasia, there have been numerous case reports concerning this disease in its primary and secondary forms. These cases have been divided into two predominant groups: the one resulting from bone marrow replacement on the basis of malignant growth or fibrosis, the other being primary or agnogenic. It has been reported in association with carcinoma metastatic to bone and with infectious states, such as scarlet fever, and in cases of generalized sepsis, tuberculosis of spleen, and idiopathic osteosclerosis. It has frequently been reported as bearing relationship to acquired hemolytic anemia. Those cases showing clinical and laboratory evidence of hemolytic anemia have been, as far as we have been able to ascertain, without exception chronic.2 We have recently had occasion to observe a case with microscopic evidence of marked myeloid metaplasia of the spleen and exhibiting an acute clinical course characterized
. . . [Full Text PDF of this Article]
Author Affiliations
WADSWORTH, KAN.
Footnotes
Dr. Claman and Dr. Collier are residents in internal medicine, Veterans Administration Hospital.
Sponsored by the Veterans Administration and published with the approval of the Chief Medical Director. The statements and conclusions published by the authors are a result of their own study and do not necessarily reflect the opinion or policy of the Veterans Administration.
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