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Report of a Case Due to Malignant Nephrosclerosis with Acute Pancreatitis

OSCAR H. COMESS, M.D.; ABE OYAMADA, M.D.

AMA Arch Intern Med. 1952;89(5):802-811.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

THE CASE described in this study presents several unusual features: 1. No other case of clinical uremia due to malignant nephrosclerosis, acute pancreatitis, and proved platelet-cell thrombosis appears in the literature. There has been one somewhat similar case without platelet-cell thrombosis reported by Gambill.¹ 2. The entity, platelet-cell thrombosis, verified at necropsy, has been reported in only about 25 cases, and in only 2 cases was the diagnosis made or suspected ante mortem.²

In the case to be presented, the diagnosis of platelet-cell thrombosis was made post mortem. Historically, the subject of pancreatic function and pancreatitis has been aptly recorded by many authors and requires little discussion here.³ In brief, acute pancreatitis was first described as a clinical entity by Fitz in 1889. Claude Bernard suggested that the cause was autodigestion due to the activation of the pancreatic enzymatic secretions. This is reflected in our present use . . . [Full Text PDF of this Article]

Author Affiliations
CHICAGO

Footnotes
Dr. Comess is on the Staff of Internal Medicine, Mount Sinai Hospital, and the Chicago Medical School. Dr. Oyamada is Resident in Pathology, Mount Sinai Hospital; Instructor, Department of Pathology, Chicago Medical School; Research Fellow in Hematology, Mount Sinai Hospital Research Foundation.

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