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Metabolic Studies on a Patient Treated with Corticotropin and Cortisone

HAROLD BROWN, M.D.; HAROLD P. HARGREAVES, M.D.; FRANK H. TYLER, M.D.

AMA Arch Intern Med. 1952;89(6):951-960.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

ALTHOUGH the diagnosis of pancreatic-cell adenoma is no longer a medical curiosity, the entity is still rare, only about 400 cases having been reported to date.¹ Moreover, the syndrome is important because it offers some clue to a more complete understanding of carbohydrate metabolism. The observation that the administration of corticotropin (ACTH) or of cortisone can correct the hypoglycemia of pancreatic hyperinsulinism² has raised the problem of the physiological mechanism of action of the hormones. The studies on our patient are germane to this problem.

REPORT OF A CASE

W. J. H. was a 58-year-old American Legion representative, who was admitted to the Salt Lake Veterans Administration Hospital on Jan. 8, 1951, for evaluation of attacks of bizarre behavior. In 1944 the patient first noticed incoordination of his hands when engaged in prolonged work. This was attributed to nervousness. During the next two years he had endured frequent . . . [Full Text PDF of this Article]

Author Affiliations
SALT LAKE CITY

From the Veterans Administration Hospital and the Departments of Medicine and Surgery, University of Utah College of Medicine.; Dr. Brown is Chief of Medicine, Veterans Administration Hospital, and Assistant Professor of Medicine, University of Utah College of Medicine. Dr. Hargreaves is Resident on Surgical Service, Veterans Administration Hospital. Dr. Tyler is Assistant Research Professor of Medicine, University of Utah College of Medicine.

Footnotes
Reviewed in the Veterans Administration and published with the approval of the Chief Medical Director. The statements and conclusions published by the authors are the result of their own study and do not necessarily reflect the opinion or policy of the Veterans Administration.

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