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ENDEMIC INFECTIOUS HEPATITIS IN AN INFANTS' ORPHANAGEEpidemiologic Studies in Infants and Small Children
ALFRED M. BENNETT, M.D.;
RICHARD B. CAPPS, M.D.;
MYLES E. DRAKE, M.D.;
RICHARD H. ETTINGER, M.D.;
ELIZABETH H. MILLS, M.S.;
JOSEPH STOKES, Jr., M.D.
AMA Arch Intern Med. 1952;90(1):37-53.
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IT HAS been known for many years that infectious hepatitis may occur in infants and small children.1 Relatively few cases, however, have been reported, and the incidence of the disease in children under 3 years of age is said to be low.2 Molner and Meyer,1e for example, in reporting on 194 children with the disease from Detroit, found only 5 between the ages of 1 and 4 years, but 77 between the ages of 5 and 9 years. Although this age differential may be due in part to residual maternal immunity or to the lack of exposure, it may also be the result of failure to recognize the disease. The degree of susceptibility would appear to be fairly high from Cookson's1h finding that 20 of 66 children, mostly under 4 years of age, in a children's nursery acquired hepatitis with jaundice.
Adequate descriptions of the clinical and laboratory findings in
. . . [Full Text PDF of this Article]
Author Affiliations
CHICAGO; PHILADELPHIA; CHICAGO; PHILADELPHIA
From the Department of Medicine, Northwestern University Medical School, and the Liver Research Laboratory of St. Luke's Hospital, Chicago (Dr. Bennett, Dr. Capps, Dr. Ettinger, and Miss Mills), and from the Department of Pediatrics, University of Pennsylvania School of Medicine and the Children's Hospital, Philadelphia (Dr. Drake and Dr. Stokes).
Footnotes
This work was done in part under a contract from the office of the Surgeon General, United States Army, and under the sponsorship of the Commission on Liver Disease, Armed Forces Epidemiological Board. Aid was also received from the Winfield Peck Memorial Fund.
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