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A Review of the Literature from September, 1950, to January, 1952

RICHARD R. EVANS, M.D.; FRANCIS M. RACKEMANN, M.D.

AMA Arch Intern Med. 1952;90(1):96-127.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

THE REVIEW of the literature on allergy from August, 1948, to September, 1950, which was published in April, 1951, by one of us,¹ discussed the nature and the actions of corticotropin (ACTH) and cortisone in their broad aspects. Since then, there have been many new studies, for the remarkable effects of these drugs have made them the object of major interest in the clinic as well as in the laboratory. Let us look first at the results of laboratory studies.

LABORATORY STUDIES

The Effect of Corticotropin and Cortisone on Immune Processes

In regard to the effect of corticotropin and cortisone on immune processes, the possibilities are several: The adrenal cortical hormone may act by inhibiting the formation of antibodies, or perhaps by inhibiting the action of those already formed. It may prevent the union of antibody with antigen; it may alter the chemical effector which results from that union, . . . [Full Text PDF of this Article]

Author Affiliations
BOSTON

From the Allergy Clinic, Massachusetts General Hospital.

Footnotes
Dr. Evans is Clinical Assistant in Medicine, and Dr. Rackemann is a member of the Board of Consultation, Massachusetts General Hospital.