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Study of Fifteen Cases

BENNETT W. BILLOW, M.D.; HARRY J. LOWEN, M.D.

AMA Arch Intern Med. 1952;90(3):310-319.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

ERYTHEMA multiforme exudativum is by no means a rare disease. Unfortunately, this malady has been reported under a variety of labels and eponyms, so that up to very recently the picture was almost a mass of utter confusion. A timely and recent editorial in The Journal of the American Medical Association¹ concerning this condition is worthy of careful perusal.

In 1860, Hebra² described a new clinical picture under the name erythema multiforme exudativum. In 1862, Alibert and Bazin³ described lesions in the mouth associated with constitutional symptoms and distinguished the herpetic lesion of the iris. In 1922, Stevens and Johnson,⁴ in describing what they called a "new eruptive fever," stressed as their criteria for diagnosis a generalized maculopapular eruption associated with ulceromembranous stomatitis, purulent conjunctivitis, and fever. In 1937, Klauder⁵ popularized in this country a new symptom complex known in the French literature as ectodermosis erosiva pluriorificialis. This was described . . . [Full Text PDF of this Article]

Author Affiliations
NEW YORK

From the Medical Service of Harlem Hospital, Dr. Alexander Altschul, Director of Medicine.

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