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L. G. WELT, M.D.; D. W. SELDIN, M.D.; W. P. NELSON III, M.D.; W. J. GERMAN, M.D.; J. P. PETERS, M.D.

AMA Arch Intern Med. 1952;90(3):355-378.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

AN INTEREST in the influence of the central nervous system on the metabolism and excretion of electrolytes and water dates back at least to the middle of the 19th century, when Bernard¹ observed a diuresis unrelated to glycosuria following puncture of a particular area of the floor of the fourth ventricle. His observation was confirmed and extended by Jungmann and Meyer.² Since that time a considerable body of data has accumulated concerning the manner in which special structures within the central nervous system respond to and participate in the control of the volume and tonicity of the body fluids. The interrelationships among these several influences are quite intimate and so ordered as to provide a series of automatic adjustments that allow a high degree of precision in the control of the several dimensions of body fluid in health and in disease.

The ingestion of those materials that comprise . . . [Full Text PDF of this Article]

Author Affiliations
CHAPEL HILL, N. C.; DALLAS, TEXAS; ALBANY, N. Y.; NEW HAVEN, CONN.

From the Departments of Internal Medicine and Surgery, Yale University School of Medicine, New Haven, Conn.

Footnotes
These investigations were supported in part by an Institutional Grant from the National Heart Institute and a Grant, H-834, from the United States Public Health Service.

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