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Analysis of Thirty-Four Cases

MARTIN A. SHEARN, M.D.; BERNARD PIROFSKY, M.D.

AMA Arch Intern Med. 1952;90(6):790-807.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

DISSEMINATED lupus erythematosus is a febrile disease of unknown etiology characterized by dermatological lesions, polyserositis, depression of the bone marrow elements, and widespread visceral involvement. It has a peculiar predilection for young women and usually has a fatal termination. In this report, a relatively large series of cases observed in a short period of time are reviewed in an attempt to present the clinical and laboratory features of the disease.

MATERIAL

Thirty-four cases of disseminated lupus erythematosus have been selected for analysis. In all the clinical course was suggestive of the diagnosis, and every case was proved by pathological examination, by the demonstration of the L. E. cell, or both. Thirty-one cases were observed in the last two years, since L. E. cell technique has been available, and the remaining three were diagnosed and proved at necropsy prior to that time. The 34 cases have been analyzed from the standpoint . . . [Full Text PDF of this Article]

Author Affiliations
NEW YORK

From the Department of Medicine, New York University Post-Graduate Medical School, and the Fourth Medical (New York University) Division, Bellevue Hospital.

Footnotes
Dr. Shearn is now at Stanford University School of Medicine, San Francisco.