This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

ALLYN B. LEY, M.D.

AMA Arch Intern Med. 1953;91(1):43-48.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

IN RECENT months several reports have appeared incriminating chloramphenicol as an etiological agent in bone marrow depression.¹ Most of these reports have described patients with an established anemia and hypoplastic marrow who gave a history of having received varying amounts of chloramphenicol.² A few have described patients in whom neutropenia developed during a course of the antibiotic.³ The present article reports serial observations on a patient who, while undergoing hematological study for other purposes, showed evidence of depression of erythropoiesis and of granulopoiesis during an episode of treatment with chloramphenicol.

REPORT OF CASE

History.

—A 51-year-old white man, an electrician, was admitted on Feb. 11, 1952, to the James Ewing Hospital with a complaint of anemia of four years' duration.

Four years before admission he consulted his local physician for a check-up, although he felt entirely well and had not sought medical consultation for the preceding 20 . . . [Full Text PDF of this Article]

Author Affiliations
NEW YORK

From the Department of Medicine, Memorial Center for Cancer and Allied Diseases, and the Division of Clinical Investigation, Sloan-Kettering Institute.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?