This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

LEWIS E. JANUARY, M.D; HENRY E. HAMILTON, M.D.; DAVID W. SINTON, M.D.

AMA Arch Intern Med. 1953;91(3):325-332.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

THE INTRAVENOUS administration of quinidine has not been accepted generally because of serious reactions following its use by this route.¹ Although intravenous quinidine preparations are known to be effective in terminating paroxysmal ventricular tachycardia,² their use has been delayed because serious sideeffects have occurred when they have been given for this purpose.³ There are few reports describing its use in a significant number of attacks of ventricular tachycardia. Hepburn and Rykert^2g recorded nine instances, and normal sinus rhythm was restored in eight. Recently Armbrust and Levine,^2a in analyzing 107 cases of paroxysmal ventricular tachycardia, described 31 attacks treated with intravenous quinidine. In 20 of the attacks, conversion to normal sinus rhythm occurred at a time which indicated a response to quinidine therapy. Herrmann and Hejtmancik^2f found it effective in two of three cases, and Clagett^2b successfully treated three patients. Strong and Munroe^2e and, more recently, Bell and his associates^2c have . . . [Full Text PDF of this Article]

Author Affiliations
IOWA CITY

From the Department of Internal Medicine, College of Medicine, State University of Iowa, Iowa City.

Footnotes
The quinidine lactate and quinidine gluconate used in this study were supplied through the courtesy of Eli Lilly & Company, Indianapolis.

Read at the 25th Annual Meeting of the Central Society for Clinical Research, Chicago, Nov. 8, 1952, and abstracted in the Proceedings of that Society (J. Lab. & Clin. Med. 40:814, 1952).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?