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IV. Report of Three Cases with Particular Reference to Asymptomatic Toxoplasma Parasitemia in a Young Woman

JOHN A. PRIOR, M.D.; CLARENCE R. COLE, D.V.M.; FRANK L. DOCTON, D.V.M.; SAMUEL SASLAW, M.D.; DEANE M. CHAMBERLAIN, D.V

AMA Arch Intern Med. 1953;92(3):314-320.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

HUMAN toxoplasmosis has been confined largely to congenital infection of infants. Acquired toxoplasmosis with clinical illness in the adult remains a rarity. On the basis of toxoplasmin skin reactivity and demonstrable circulating antibodies there is increasing evidence of widespread infection in man without clinical manifestations.

As a result of the development of a new serologic method of diagnosis,¹ long series of infants and children with congenital toxoplasmosis have been reported. Sabin and Feldman² reported 23 patients with congenital disease in 1948. Eichenwald³ established the diagnosis for 100 patients from 1948 to 1952, and Feldman³ found 75 patients from 1949 to 1952. Careful interrogation has uniformly failed to elicit any history of illness attributable to toxoplasmosis, either present or past, in the mothers of infants so affected. However, the mothers of infants with toxoplasmosis always show high Toxoplasma antibody titers, indicative of recent infection. Therefore, it is logical to assume that . . . [Full Text PDF of this Article]

Author Affiliations
COLUMBUS, OHIO

From the Departments of Medicine and Veterinary Pathology, Ohio State University.

Footnotes
This investigation was supported in part by a research grant from the National Institutes of Health, Public Health Service.

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