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Report of a Case with Pharmacologic Tests, Roentgenologic Diagnosis, and Endocrine Survey

EUGENE B. LEVIN, M.D.

AMA Arch Intern Med. 1953;92(6):906-919.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

ALTHOUGH many excellent articles¹ continue to review the literature of cases of paroxysmal hypertension produced by adrenal medulla tumors, little has been mentioned about the various endocrine manifestations of this condition. This paper, in addition to discussing the pharmacologic and roentgenographic means of diagnosis, will specifically emphasize the various endocrine findings and their significance.

Selye² first called attention to the effects of stress on the adrenal-pituitary axis. Further work pointed to a specific relationship between epinephrine and this axis. Experimentation with epinephrine administration in animals and later in man resulted in a decrease in the circulating eosinophiles, decrease in adrenal ascorbic acid and cholesterol levels, and an increase in 17-ketosteroid excretion in the urine.³ From these findings a test has been devised using subcutaneous injection of epinephrine to ascertain the integrity of this system.^3a In cases of pheochromocytoma, in which epinephrine and arterenol (norepinephrine) have been found intermittently or constantly . . . [Full Text PDF of this Article]

Author Affiliations
SAN FRANCISCO

Footnotes
Formerly Resident in Internal Medicine at the Veterans Administration Hospital, Long Beach, California. Now in the United States Army.

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