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STUDIES ON SERUM CHOLESTEROL AND OTHER CHARACTERISTICS OF CLINICALLY HEALTHY MEN IN NAPLES
ANCEL KEYS, Ph.D.;
FLAMINIO FIDANZA, M.D.;
VICENZO SCARDI, D.Sc.;
GINO BERGAMI, M.D.;
MARGARET HANEY KEYS, A.B.;
FERRUCCIO DI LORENZO
AMA Arch Intern Med. 1954;93(3):328-336.
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IN THE control of the concentration of blood cholesterol the diet clearly has a marked and ubiquitous effect, but the picture differs in various species. Man does not compare with the rabbit and the chick in sensitivity to exogenous cholesterol, but his response to total fats in the diet appears to be greater.* Obviously, quantitative information on the effect of the diet on the blood cholesterol level in man must be sought from man himself.
Experiments on this problem in man generally have several defects. The studies reported so far have largely ignored the important factor of age 7 and have been limited to a few weeks or months of drastic change from previous lifelong subsistence on the relatively high-fat diet that is almost universally used in the United States at the present time.
The present paper reports findings on clinically healthy men in Naples, where the habitual diet, like
. . . [Full Text PDF of this Article]
Author Affiliations
MINNEAPOLIS; NAPLES, ITALY; MINNEAPOLIS; NAPLES, ITALY
From the Laboratory of Physiological Hygiene, School of Public Health, University of Minnesota, and the Institutes of Physiology and of Biochemistry, Faculty of Medicine, University of Naples.
Footnotes
Dr. Keys was a Senior Fulbright Fellow (Research) during the time when the data were collected in Naples.
The work reported here was materially aided by a research grant to the senior author from the National Dairy Council, Chicago.
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